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Fig. 13: QF-DE of early endosome with coated buds

Quick-freeze deep-etch rotary-shadowed replica of an early endosome with two clathrin-coated evaginations (arrowheads). Presumably these coated pits contain receptors for cargo that will be pinched off from the early endosomes and passed on through carrier vesicles to the late endosomal compartments (see Digestive Vacuole Chapter for late endosomes and their fate). Early endosomes lie at the level of the intraciliary lattice (il) and proximal ends of basal bodies (bb), but internal to the striated bands (sb). Piam, P-face of inner alveolar membrane. EM taken on 6/4/91 by R. Allen with Zeiss 10A TEM. Neg. 19,800X. Bar = 0.25µm. Published in J. Cell Sci. 101:449-461, 1992.
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