Home   Chapter 6

56-pmdv790413-29

Fig. 56: lysosomal membrane retrieval following digestion

Following digestion, that only occurs in the phagolysosome (DV-III), the membrane of these DVs undergoes extensive tubulation. These tubules are ~45nm in diameter and arise from the cytosolic surface of the DV-III in clumps of 3 to 6 tubules per clump. The tubules contain a glycocalyx-like lining in their lumens which leaves only a 10nm diameter opening in the center of the tubule (see Allen and Fok, J. Cell Biol. 99:1955-1959, 1984). EM taken on 4/13/79 by R. Allen with Hitachi HU11A TEM. Neg. 14,750X. Bar = 0.25µm.
Download High Resolution TIF Image (4.6 MB)