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50-pmdv82

Fig. 50: freeze fracture of early DV-III membrane surrounded by some lysosomes and many smaller vesicles

A freeze-fracture image of a DV-II transforming into a DV-III by rapid fusion of lysosomes with its membrane. The P-face shown here of the early DV-III has abundant IMPs as well as many inward blebs (many are fractured off) and a wrinkled surface topography indicating recent lysosome fusion with the membrane. Some lysosomes (ly) still lie around the DV as well as many smaller vesicles (arrowheads). Blebs however only extend inward toward the lumen rather than into the cytosol. EM taken on 9/27/76 by R. Allen with JEM-100B TEM. Neg. 9,719X. Bar = 0.5µm.
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