Secondary lysosomes contain a fairly dense matrix in well fixed cells. The content of these lysosomes seems to be released as a package into the phagoacidosome when they fuse to form the phagolysosome. Secondary lysosomes contain both hydrolases and substrate. The appearance of HRP (as in Figure 35) shows that some substrates have access to these secondary lysosomes. EM taken on 4/19/79 by R. Allen with Hitachi HU11A TEM. Neg. 10,000X. Bar = 0.5µm. |
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