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Acid phosphatase is synthesized in the biosynthetic pathway in the ER
(er) and packaged in the TGN into primary lysosomes which are
passed on to secondary lysosomes. Primary lysosomes are small vesicles
of 75-100nm filled with acid phosphatase and no substrate. They
probably fuse with secondary lysosomes before the secondary lysosomes
fuse with the DV-II. Small vesicles of the size of primary lysosomes
are near secondary lysosomes in Figure 40. EM taken on 3/26/79 by J.
Muraoka with Hitachi HU11A TEM. Neg. 25,500X. Bar = 0.2µm.
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